LGR5 (leucine-rich repeat containing G protein-coupled receptor 5) is a protein-coding gene. GO annotations related to this gene include transmembrane signaling receptor activity and G-protein coupled receptor activity. An important paralog of this gene is LHCGR. …
Miscellaneous. LGR5 is used as a marker of adult tissue stem cells in the intestine, stomach, hair follicle, and mammary epithelium.1 Publication.
Manually curated information which has been inferred by a curator based on his/her scientific knowledge or on the scientific content of an article.
The knowledgebase automatically integrates gene-centric data from ~150 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information. A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site via CRISPR/Cas9 mediated recombination. Gene: LGR5; leucine rich repeat containing G protein-coupled receptor 5: Aliases: FEX, HG38, GPR49, GPR67, GRP49 : Location: 12q21.1: Summary: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. PrimePCR™ PreAmp for SYBR® Green Assay: LGR5, Human Reaction: 400 reactions Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.
-0.28. IFITM2. 0.55. -0.40. TRIM21. Manually curated information which has been inferred by a curator based on his/her scientific knowledge or on the scientific content of an article. av N Knuutinen · 2020 — associated with loss-of-function of the tumor suppressor gene APC. delande Lgr5-positiva (Lgr5+) stamceller är belägna längst nere i kryptorna blandat. Visar resultat 1 - 5 av 6 avhandlingar innehållade orden LGR5 stem cells. findings about the mechanism of action of FoxF genes in development and disease. A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site via CRISPR/Cas9 mediated recombination. Gene: LGR5; leucine rich repeat containing G protein-coupled receptor 5: Aliases: FEX, HG38, GPR49, GPR67, GRP49 : Location: 12q21.1: Summary: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries. Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all spec
Expression of LGR5 in cancer - Summary - The Human Protein Atlas. Discover Lgr5's significant phenotypes, expression, images, histopathology and more. Data for gene Lgr5 is all freely available for download. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR. -0.40. TRIM21. LGR5 (HGNC Symbol) Synonyms. FEX, GPR49, GPR67, HG38: Description.
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Lgr5 was originally discovered as a common Wnt target gene in adult intestinal Rnf43/Znrf3 are themselves encoded by Wnt target genes and constitute a
Oct 22, 2010 The expression of LGR5 is induced in the limb, tail, and intestine by T3 during metamorphosis. More importantly, LGR5 mRNA is localized to the
Mar 5, 2021 GeneCards Summary for LGR5 Gene. LGR5 (Leucine Rich Repeat Containing G Protein-Coupled Receptor 5) is a Protein Coding gene.
Miscellaneous. LGR5 is used as a marker of adult tissue stem cells in the intestine, stomach, hair follicle, and mammary epithelium.1 Publication.
LGR5_ENST00000540815 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, LGR5_ENST00000540815 Genome Browser, LGR5_ENST00000540815 References LGR5_ENST00000540815 - Explore an overview of LGR5_ENST00000540815, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.
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General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. LGR5. Gene descriptioni.